Multifocal stimulation of the cerebro-cerebellar loop during the acquisition of a novel motor skill.

ABSTRACT: Transcranial direct current stimulation (tDCS)-based interventions for augmenting motor learning are gaining interest in systems neuroscience and clinical research. Current approaches focus largely on monofocal motorcortical stimulation. Innovative stimulation protocols, accounting for motor learning related brain network interactions also, may further enhance effect sizes. Here, we tested different stimulation approaches targeting the cerebro-cerebellar loop. Forty young, healthy participants trained a fine motor skill with concurrent tDCS in four sessions over two days, testing the following conditions: (1) monofocal motorcortical, (2) sham, (3) monofocal cerebellar, or (4) sequential multifocal motorcortico-cerebellar stimulation in a double-blind, parallel design. Skill retention was a

SUBMITTER: Wessel MJ 

PROVIDER: S-EPMC7815761 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature