Bioimage Analysis and Cell Motility.

ABSTRACT: Bioimage analysis (BIA) has historically helped study how and why cells move; biological experiments evolved in intimate feedback with the most classical image processing techniques because they contribute objectivity and reproducibility to an eminently qualitative science. Cell segmentation, tracking, and morphology descriptors are all discussed here. Using ameboid motility as a case study, these methods help us illustrate how proper quantification can augment biological data, for example, by choosing mathematical representations that amplify initially subtle differences, by statistically uncovering general laws or by integrating physical insight. More recently, the non-invasive nature of quantitative imaging is fertilizing two blooming fields: mechanobiology, where many bio

SUBMITTER: Boquet-Pujadas A 

PROVIDER: S-EPMC7815951 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature