Chromatin-associated SUMOylation controls the transcriptional switch between plant development and heat stress responses.

ABSTRACT: The post-translational protein modification known as SUMOylation has conserved roles in the heat stress responses of various species. The functional connection between the global regulation of gene expression and chromatin-associated SUMOylation in plant cells is unknown. Here, we uncovered a genome-wide relationship between chromatin-associated SUMOylation and transcriptional switches in Arabidopsis thaliana grown at room temperature, exposed to heat stress, and exposed to heat stress followed by recovery. The small ubiquitin-like modifier (SUMO)-associated chromatin sites, characterized by whole-genome ChIP-seq, were generally associated with active chromatin markers. In response to heat stress, chromatin-associated SUMO signals increased at promoter-transcriptional start site reg

SUBMITTER: Han D 

PROVIDER: S-EPMC7816078 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature