Association of Maternal Autoimmune Disease With Attention-Deficit/Hyperactivity Disorder in Children.

ABSTRACT:

Importance

Maternal autoimmune disease has been associated with increased risk of neurodevelopmental disorders in offspring, but few studies have assessed the association with attention-deficit/hyperactivity disorder (ADHD).

Objective

To examine the association between maternal autoimmune disease and ADHD within a population-based cohort and combine results in a subsequent systematic review and meta-analysis.

Design, setting, and participants

A cohort study was conducted of singleton children born at term gestation (37-41 weeks) in New South Wales, Australia, from July 1, 2000, to December 31, 2010, and followed up until the end of 2014; and a systematic review evaluated articles from the MEDLINE, Embase, and Web of Science databases to identify all studies published

SUBMITTER: Nielsen TC 

PROVIDER: S-EPMC7816116 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature