Clinical course and challenging management of early COVID-19 infection after heart transplantation: case report of two patients.

ABSTRACT:

Background

There are limited data on Coronavirus disease 2019 (COVID-19) in solid organ transplant patients, especially in heart transplant recipients, with only a few case reports and case series described so far. Heart transplant recipients may be at particular high risk due to their comorbidities and immunosuppressed state.

Case presentation

This report describes the clinical course and the challenging management of early COVID-19 infection in two heart transplant recipients who tested positive for the SARS-CoV-2 virus in the perioperative period of the transplant procedure. The two patients developed a severe form of the disease and ultimately died despite the initiation of an antiviral monotherapy with hydroxychloroquine coupled with the interruption of mycophenolate mo

SUBMITTER: Tchana-Sato V 

PROVIDER: S-EPMC7816134 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature