Ambient air pollution exposure during the late gestational period is linked with lower placental iodine load in a Belgian birth cohort.

ABSTRACT:

Background

Adequate intake of iodine is required for the production of thyroid hormones and contributes in pregnant women to a healthy brain development and growth in their offspring. To date, some evidence exists that fine particulate air pollution is linked with the fetal thyroid hormone homeostasis. However, possible effects of air pollutants on the placental iodine storage have not been investigated so far.

Objectives

We investigated the association between air pollution exposure to particulate matter with a diameter less than 2.5 µm (PM_2.5), NO₂, and black carbon and the placental iodine load.

Methods

The current study is part of the ENVIRONAGE birth cohort and included 470 mother-newborn pairs. Iodine concentrations were measured in placent

SUBMITTER: Neven KY 

PROVIDER: S-EPMC7816215 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature