Focused ultrasound robotic system for very small bore magnetic resonance imaging.

ABSTRACT:

Background

A magnetic resonance imaging (MRI) compatible robotic system for focused ultrasound was developed for small animal like mice or rats that fits into a 9.4 T MRI scanner (Bruker Biospec 9420, Bruker Biospin, Ettlingen, Germany). The robotic system includes two computer-controlled linear stages.

Materials and methods

The robotic system was evaluated in a mouse-shaped, real-size agar-based mimicking material, which has similar acoustical properties as soft tissues. The agar content was 6% weight per volume (w/v), 4% w/v silica while the rest was degassed water. The transducer used has a diameter of 4 cm, operates with 2.6 MHz and focuses energy at 5 cm.

Results

The MRI compatibility of the robotic system was evaluated in a 9.4 T small animal scanner. The effica

SUBMITTER: Damianou C 

PROVIDER: S-EPMC7816236 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature