Deciphering the miRNA transcriptome of breast muscle from the embryonic to post-hatching periods in chickens.

ABSTRACT:

Background

miRNAs play critical roles in growth and development. Various studies of chicken muscle development have focused on identifying miRNAs that are important for embryo or adult muscle development. However, little is known about the role of miRNAs in the whole muscle development process from embryonic to post-hatching periods. Here, we present a comprehensive investigation of miRNA transcriptomes at 12-day embryo (E12), E17, and day 1 (D1), D14, D56 and D98 post-hatching stages.

Results

We identified 337 differentially expressed miRNAs (DE-miRNAs) during muscle development. A Short Time-Series Expression Miner analysis identified two significantly different expression profiles. Profile 4 with downregulated pattern contained 106 DE-miRNAs, while profile 21 with upregul

SUBMITTER: Liu J 

PROVIDER: S-EPMC7816426 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature