Head of bed elevation to relieve gastroesophageal reflux symptoms: a systematic review.

ABSTRACT:

Background

Overuse of proton pump inhibitors (PPIs) - frequently used for relieving symptoms of gastroesophageal reflux disease (GORD) - raises long-term safety concerns, warranting evidence-based non-drug interventions. We conducted a systematic review to evaluate the effect of head-of-bed elevation on relieving symptoms of GORD in adults.

Methods

We included controlled trials comparing the effect of head-of-bed elevation interventions to control in adults with GORD. Two independent reviewers screened articles, extracted data, and assessed quality of included studies. Primary outcomes were changes in GORD symptoms and use of PPIs.

Results

We screened 1206 records; and included five trials (four cross-over and one factorial) comprising 228 patients. All five included

SUBMITTER: Albarqouni L 

PROVIDER: S-EPMC7816499 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature