Sex Differences in Demand for Highly Palatable Foods: Role of the Orexin System.

ABSTRACT:

Background

The prevalence of eating disorders, including binge eating disorder, is significantly higher in women. These findings are mirrored by preclinical studies, which indicate that female rats have a higher preference for palatable food and show greater binge-like eating compared with male rats.

Methods

Here, we describe a novel within-session behavioral-economic paradigm that allows for the simultaneous measurement of the intake at null cost (Q0) and normalized demand elasticity (α) of 3 types of palatable food (low fat, high fat, and chocolate sucrose pellets) via demand curve analysis. In light of evidence that the orexin (hypocretin) system is critically involved in reward and feeding behaviors, we also examined the role of orexin function in sex differences of econ

SUBMITTER: Freeman LR 

PROVIDER: S-EPMC7816693 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature