Correlation between Lsp1 (Rs3817198) and Casc (Rs4784227) Polymorphisms and the Susceptibility to Breast Cancer.

ABSTRACT:

Background

Breast cancer is classified as one of the common cancers among women worldwide. Within numerous genetic factors involved in the development of breast cancer, lsp1 and casc genes are both located on breast cancer susceptibility locus. While the SNP rs3817198 in lsp1 gene has a twilight association with breast cancer in different populations, casc rs4784227 polymorphisms have been reported to associate with breast tumor appearance in Asian, European, and African ancestry populations. The present report was designed a case-control group aimed at assessing the association of these two SNPs with breast cancer risk in the Iranian population.

Methods

In the case-control study of rs3817198 and rs4784227 polymorphisms in 100

SUBMITTER: Nourolahzadeh Z 

PROVIDER: S-EPMC7816788 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature