A universal RT-qPCR assay for "One Health" detection of influenza A viruses.

ABSTRACT: The mutual dependence of human and animal health is central to the One Health initiative as an integrated strategy for infectious disease control and management. A crucial element of the One Health includes preparation and response to influenza A virus (IAV) threats at the human-animal interface. The IAVs are characterized by extensive genetic variability, they circulate among different hosts and can establish host-specific lineages. The four main hosts are: avian, swine, human and equine, with occasional transmission to other mammalian species. The host diversity is mirrored in the range of the RT-qPCR assays for IAV detection. Different assays are recommended by the responsible health authorities for generic IAV detection in birds, swine or humans. In order to unify IAV monitoring in dif

SUBMITTER: Nagy A 

PROVIDER: S-EPMC7817021 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature