Predictors of intubation in COVID-19 patients treated with out-of-ICU continuous positive airway pressure.

ABSTRACT:

Background

As delayed intubation may worsen the outcome of coronavirus disease 2019 (COVID-19) patients treated with continuous positive airway pressure (CPAP), we sought to determine COVID-specific early predictors of CPAP failure.

Methods

In this observational retrospective multicentre study, we included all COVID-19 patients treated with out-of-ICU CPAP, candidates for intubation in case of CPAP failure. From these patients, we collected demographic and clinical data.

Results

A total of 397 COVID-19 patients were treated with CPAP for respiratory failure, with the therapeutic goal of providing intubation in case of CPAP failure. Univariable analysis showed that, age, lactate dehydrogenase (LDH) and white cell counts were all significantly lower in patients with suc

SUBMITTER: De Vita N 

PROVIDER: S-EPMC7817479 | biostudies-literature | 2022 May-Jun

REPOSITORIES: biostudies-literature