Prediction of early recurrence of hepatocellular carcinoma after resection using digital pathology images assessed by machine learning.

ABSTRACT: Hepatocellular carcinoma (HCC) is a representative primary liver cancer caused by long-term and repetitive liver injury. Surgical resection is generally selected as the radical cure treatment. Because the early recurrence of HCC after resection is associated with low overall survival, the prediction of recurrence after resection is clinically important. However, the pathological characteristics of the early recurrence of HCC have not yet been elucidated. We attempted to predict the early recurrence of HCC after resection based on digital pathologic images of hematoxylin and eosin-stained specimens and machine learning applying a support vector machine (SVM). The 158 HCC patients meeting the Milan criteria who underwent surgical resection were included in this study. The patients were categ

SUBMITTER: Saito A 

PROVIDER: S-EPMC7817520 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature