Prevalence and genotype distribution of group A rotavirus circulating in Shanxi Province, China during 2015-2019.

ABSTRACT:

Background

Group A rotavirus (RVA), despite being a leading cause of gastroenteritis in infants and young children, is less studied in Shanxi Province, China. The current study was conducted to determine the prevalence and genetic characterization of RVA in hospitalized children younger than 10 years of age with the diagnosis of acute gastroenteritis in Shanxi Province, China.

Methods

A hospital-based active surveillance of rotavirus gastroenteritis was conducted at Children's Hospital of Shanxi from Jan 1, 2015, through Dec 31, 2019. Rotavirus was detected in stool samples by real-time quantitative reverse transcription PCR (qRT-PCR). G- and P-genotypes were determined by reverse transcription PCR (RT-PCR) and nucleotide sequencing.

Results

A total of 961 children yo

SUBMITTER: Zhao L 

PROVIDER: S-EPMC7818068 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature