Increased atrial fibrillation risk in Parkinson's disease: A nationwide population-based study.

ABSTRACT:

Objective

Parkinson's disease (PD) is the second most common neurodegenerative disorder associated with various morbidities. Although the relationship between cardiovascular disease and PD has been studied, a paucity of information on PD and atrial fibrillation (AF) association exists. Thus, we aimed to investigate whether patients with PD have an increased risk of AF.

Methods

This study included 57,585 patients with newly diagnosed PD (≥40-year-old, mean age 69.7 years, men 40.2%) and without a history of AF from the Korean National Health Insurance Service (NHIS) database between 2010 and 2015. Furthermore, an equal number of age- and sex-matched subjects without PD were selected for comparison. The primary outcome was new-onset AF.

Results

During the mean follow-up

SUBMITTER: Han S 

PROVIDER: S-EPMC7818085 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature