Neuropsychiatric comorbidities in Huntington's and Parkinson's Disease: A United States claims database analysis.

ABSTRACT:

Objective

Huntington's disease is a rare, genetic, neurodegenerative disease characterized by a triad of cognitive, behavioral, and motor symptoms. The condition gradually results in increasing disability, loss of independence, and ultimately death. Our objective was to use United States claims data (which offer valuable insight into the natural history of disease) to compare the prevalent comorbidities of people with Huntington's disease against matched controls with Parkinson's disease or with no major neurodegenerative diseases (general population controls). We also assess medication use in people with Huntington's disease.

Methods

This was a retrospective, observational study using data from the IBM MarketScan^® Databases. Cases and controls were matched 1:1, a

SUBMITTER: Ishihara L 

PROVIDER: S-EPMC7818185 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature