Low-molecular weight heparin prevents portal vein system thrombosis after splenectomy: a systematic review and meta-analysis.

ABSTRACT:

Background

The aim of this study was to evaluate the safety and efficacy of low-molecular weight heparin (LMWH) in the prevention of portal vein system thrombosis (PVST) after splenectomy.

Methods

A systematic search was performed using PubMed, EMBASE, Springer and Cochrane Library databases to screen out studies comparing the prognoses between post-splenectomy patients treated with and without LMWH. The incidences of PVST and bleeding complications were used as parameters to assess the effect of LMWH.

Results

Six articles met the selection criteria and were included in this study. A total of 740 patients were involved in these six articles, including 336 patients treated with LMWH (LMWH group) and 385 patients not treated with LMWH (control group). The incidence of P

SUBMITTER: Yang M 

PROVIDER: S-EPMC7818250 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature