Magnetoelectric Materials for Miniature, Wireless Neural Stimulation at Therapeutic Frequencies.

ABSTRACT: A major challenge for miniature bioelectronics is wireless power delivery deep inside the body. Electromagnetic or ultrasound waves suffer from absorption and impedance mismatches at biological interfaces. On the other hand, magnetic fields do not suffer these losses, which has led to magnetically powered bioelectronic implants based on induction or magnetothermal effects. However, these approaches have yet to produce a miniature stimulator that operates at clinically relevant high frequencies. Here, we show that an alternative wireless power method based on magnetoelectric (ME) materials enables miniature magnetically powered neural stimulators that operate up to clinically relevant frequencies in excess of 100 Hz. We demonstrate that wireless ME stimulators provide therapeutic deep brain

SUBMITTER: Singer A 

PROVIDER: S-EPMC7818389 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature