Ontology highlight
ABSTRACT:
SUBMITTER: Pols T
PROVIDER: S-EPMC7818446 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Pols Tjeerd T Singh Shubham S Deelman-Driessen Cecile C Gaastra Bauke F BF Poolman Bert B
The FEBS journal 20200505 1
In cells, the breakdown of arginine to ornithine and ammonium ion plus carbon dioxide is coupled to the generation of metabolic energy in the form of ATP. The arginine breakdown pathway is minimally composed of arginine deiminase, ornithine transcarbamoylase, carbamate kinase, and an arginine/ornithine antiporter; ammonia and carbon dioxide most likely diffuse passively across the membrane. The genes for the enzymes and transporter have been cloned and expressed, and the proteins have been purif ...[more]