Association of smoking reduction and mortality: protocol for a systematic review and meta-analysis of longitudinal observational studies.

ABSTRACT:

Introduction

Strong evidence shows that smoking cessation decreases mortality. Much less is known regarding the association between reduction in cigarettes per day (CPD) and mortality. The primary aim of this systematic review is to compare the mortality risk between smokers achieving a sustained reduction of CPD and smokers maintaining their smoking rate. The secondary aims are to compare the mortality risk between smokers achieving complete, sustained smoking cessation and (1) smokers maintaining their smoking rate and (2) smokers who achieved a sustained reduction in smoking rate.

Methods and analysis

MEDLINE, Web of Sciences and Embase will be searched using a prespecified search strategy, up to 23 November 2020, and will be limited to studies published in English and in

SUBMITTER: Aubin HJ 

PROVIDER: S-EPMC7818821 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature