Mechanisms of neuroplasticity and brain degeneration: strategies for protection during the aging process.

ABSTRACT: Aging is a dynamic and progressive process that begins at conception and continues until death. This process leads to a decrease in homeostasis and morphological, biochemical and psychological changes, increasing the individual's vulnerability to various diseases. The growth in the number of aging populations has increased the prevalence of chronic degenerative diseases, impairment of the central nervous system and dementias, such as Alzheimer's disease, whose main risk factor is age, leading to an increase of the number of individuals who need daily support for life activities. Some theories about aging suggest it is caused by an increase of cellular senescence and reactive oxygen species, which leads to inflammation, oxidation, cell membrane damage and consequently neuronal death. Also,

SUBMITTER: Toricelli M 

PROVIDER: S-EPMC7818866 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature