Interventricular Septal Rupture in a 62-Year-Old Man With Familial Amyloid Polyneuropathy.

ABSTRACT: Cardiac involvement in familial amyloid polyneuropathy consists of arrhythmias, conduction disturbances, and heart failure. To our knowledge, heart rupture has never been described in association with this condition. We report the case of a 62-year-old man with a 6-year history of refractory familial amyloid polyneuropathy who underwent liver transplantation. The operation was complicated by severe hypotension because the neuropathy involved the autonomic system. Perioperatively, the patient had a myocardial infarction, and during the next 10 days, a complete interventricular septal rupture developed, resulting in a systemic-to-pulmonary shunt. Coronary angiographic findings were normal. However, the shunt caused unstable hemodynamics, resulting in cardiogenic shock. An attempt to close th

SUBMITTER: Pidello S 

PROVIDER: S-EPMC7819432 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature