Impact of Intrapartum Oral Azithromycin on the Acquired Macrolide Resistome of Infants' Nasopharynx: A Randomized Controlled Trial.

ABSTRACT: In a post hoc analysis of samples from an intrapartum azithromycin randomized clinical trial, we found that children whose mothers had been treated with the drug had higher prevalence of macrolide-resistance genes msr(A) and ermC at 28 days but not at 12 months. The 2 genes were positively associated in the nasopharynx.

Clinical trials registration

NCT1800942.

SUBMITTER: Bojang A 

PROVIDER: S-EPMC7819521 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature