Assessment of insulin sensitivity during hyperbaric oxygen treatment.

ABSTRACT:

Introduction

Previous studies using a hyperinsulinaemic, euglycaemic glucose clamp have demonstrated an increase in peripheral insulin sensitivity in men with and without Type-2 diabetes mellitus on the third and thirtieth hyperbaric oxygen treatment (HBOT) session. In two studies using different techniques for assessment of insulin sensitivity, we investigated the onset and duration of this insulin-sensitising effect of HBOT.

Methods

Men who were obese or overweight but without diabetes were recruited. One study performed a hyperinsulinaemic euglycaemic glucose clamp (80 mU.m^-2.min^-1) at baseline and during the first HBOT exposure (n = 9) at a pressure of 203 kPa. Data were analysed by paired t-test. The other study assessed insulin sensitivity by a fr

SUBMITTER: Wilkinson D 

PROVIDER: S-EPMC7819732 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature