Recording site placement on planar silicon-based probes affects signal quality in acute neuronal recordings.

ABSTRACT: Multisite, silicon-based probes are widely used tools to record the electrical activity of neuronal populations. Several physical features of these devices are designed to improve their recording performance. Here, our goal was to investigate whether the position of recording sites on the silicon shank might affect the quality of the recorded neural signal in acute experiments. Neural recordings obtained with five different types of high-density, single-shank, planar silicon probes from anesthetized rats were analyzed. Wideband data were filtered to extract spiking activity, then the amplitude distribution of samples and quantitative properties of the recorded brain activity (single unit yield, spike amplitude and isolation distance) were compared between sites located at different positio

SUBMITTER: Fiath R 

PROVIDER: S-EPMC7819990 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature