Evaluation on reprogramed biological processes in transgenic maize varieties using transcriptomics and metabolomics.

ABSTRACT: Genetic engineering (GM) has great potential to improve maize productivity, but rises some concerns on unintended effects, and equivalent as their comparators. There are some limitations through targeted analysis to detect the UE in genetically modified organisms in many previous studies. We here reported a case-study on the effects of introducing herbicides and insect resistance (HIR) gene cassette on molecular profiling (transcripts and metabolites) in a popular maize variety Zhengdan958 (ZD958) in China. We found that introducing HIR gene cassette bring a limited numbers of differential abundant genes (DAGs) or differential abundant metabolites (DAMs) between transgenic events and non-transgenic control. In contrast, averaged 10 times more DAGs and DAMs were observed when performed comp

SUBMITTER: Fu W 

PROVIDER: S-EPMC7820507 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature