Nanohole-boosted electron transport between nanomaterials and bacteria as a concept for nano-bio interactions.

ABSTRACT: Biofilms contribute to bacterial infection and drug resistance and are a serious threat to global human health. Antibacterial nanomaterials have attracted considerable attention, but the inhibition of biofilms remains a major challenge. Herein, we propose a nanohole-boosted electron transport (NBET) antibiofilm concept. Unlike known antibacterial mechanisms (e.g., reactive oxygen species production and cell membrane damage), nanoholes with atomic vacancies and biofilms serve as electronic donors and receptors, respectively, and thus boost the high electron transport capacity between nanomaterials and biofilms. Electron transport effectively destroys the critical components (proteins, intercellularly adhered polysaccharides and extracellular DNA) of biofilms, and the nanoholes also signific

SUBMITTER: Shi T 

PROVIDER: S-EPMC7820612 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature