Incidence and risk factors for osteoporotic fractures in patients with systemic lupus erythematosus versus matched controls.

ABSTRACT:

Background/aims

Despite recent improvements in the quality of life of patients with systemic lupus erythematosus (SLE), osteoporosis, and osteoporotic fractures are one of the major complications of SLE. Furthermore, limited data are available on the incidence and predictor of osteoporotic fractures in Korean patients with SLE. Herein, we aimed to assess the incidence and risk factors for osteoporotic fractures in Korean SLE patients compared to those without SLE.

Methods

SLE patients aged ≥ 40 years (n = 10,434; mean age, 51.3 ± 9.1 years; women, 89.7%) were selected from the Korean National Health Insurance Service database, spanning a period from 2008 to 2014. Age- and sex-matched controls (n = 52,170) were randomly sampled in a 5:1 ratio from non-SLE individuals. The pri

SUBMITTER: Kim CS 

PROVIDER: S-EPMC7820659 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature