Sex Differences in Immunity: Implications for the Development of Novel Vaccines Against Emerging Pathogens.

ABSTRACT: Vaccines are one of the greatest public health achievements and have saved millions of lives. They represent a key countermeasure to limit epidemics caused by emerging infectious diseases. The Ebola virus disease crisis in West Africa dramatically revealed the need for a rapid and strategic development of vaccines to effectively control outbreaks. Seven years later, in light of the SARS-CoV-2 pandemic, this need has never been as urgent as it is today. Vaccine development and implementation of clinical trials have been greatly accelerated, but still lack strategic design and evaluation. Responses to vaccination can vary widely across individuals based on factors like age, microbiome, co-morbidities and sex. The latter aspect has received more and more attention in recent years and a growin

SUBMITTER: Fathi A 

PROVIDER: S-EPMC7820860 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature