Association of Race/Ethnicity and the 21-Gene Recurrence Score With Breast Cancer-Specific Mortality Among US Women.

ABSTRACT:

Importance

Given the widespread use of the 21-gene recurrence score for identifying candidates for adjuvant chemotherapy, it is important to examine the performance of the Oncotype DX Breast Recurrence Score test in diverse patient populations to validate this approach for tailoring treatment in women in racial/ethnic minority groups.

Objective

To examine whether breast cancer-specific mortality for women with hormone-dependent breast cancer differs by race/ethnicity across risk categories defined by the Oncotype DX Breast Recurrence Score test and whether the prognostic accuracy of the 21-gene recurrence score differs by race/ethnicity.

Design, setting, and participants

This retrospective, population-based cohort study used the Surveillance, Epidemiology, and End Res

SUBMITTER: Hoskins KF 

PROVIDER: S-EPMC7821091 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature