Risk factors for the COVID-19 severity and its correlation with viral shedding: A retrospective cohort study.

ABSTRACT: Coronavirus disease 2019 (COVID-19) have become a pandemic in the world. This study is aim to explore risk factors for COVID-19 severity in the early stage and the correlation between the viral shedding and COVID-19 severity. We included inpatient with laboratory confirmed COVID-19 who had been discharged by 9 March 2020. The medical record data and dynamic change of biochemical indicators in-hospital were compared between common and severe patients. Eighty patients were included in this study. Multivariable regression demonstrated increasing odds of severity associated with the duration of fever (odds ratio [OR], 1.42; 95% confidence interval [CI], 1.10-1.82, per day increase; P = .007), C-reactive protein (CRP) (OR, 1.26; 95% CI, 1.04-1.52; P = .02), and PO₂  < 80 mm Hg (28.07

SUBMITTER: Zheng X 

PROVIDER: S-EPMC7821149 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature