SNF-NN: computational method to predict drug-disease interactions using similarity network fusion and neural networks.

ABSTRACT:

Background

Drug repositioning is an emerging approach in pharmaceutical research for identifying novel therapeutic potentials for approved drugs and discover therapies for untreated diseases. Due to its time and cost efficiency, drug repositioning plays an instrumental role in optimizing the drug development process compared to the traditional de novo drug discovery process. Advances in the genomics, together with the enormous growth of large-scale publicly available data and the availability of high-performance computing capabilities, have further motivated the development of computational drug repositioning approaches. More recently, the rise of machine learning techniques, together with the availability of powerful computers, has made the area of computational drug repositioning

SUBMITTER: Jarada TN 

PROVIDER: S-EPMC7821180 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature