Ontology highlight
ABSTRACT:
SUBMITTER: van Doeveren T
PROVIDER: S-EPMC7821318 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
International journal of cancer 20201013 4
The risk of developing urothelial carcinoma of the bladder (UCB) in patients treated by radical nephroureterectomy (RNU) for an upper urinary tract urothelial carcinoma (UTUC) is 22% to 47% in the 2 years after surgery. Subject of debate remains whether UTUC and the subsequent UCB are clonally related or represent separate origins. To investigate the clonal relationship between both entities, we performed targeted DNA sequencing of a panel of 41 genes on matched normal and tumor tissue of 15 pri ...[more]