Diagnostic efficiency of whole-body ¹⁸F-FDG PET/MRI, MRI alone, and SUV and ADC values in staging of primary uterine cervical cancer.

ABSTRACT:

Background

The use of PET/MRI for gynecological cancers is emerging. The purpose of this study was to assess the additional diagnostic value of PET over MRI alone in local and whole-body staging of cervical cancer, and to evaluate the benefit of standardized uptake value (SUV) and apparent diffusion coefficient (ADC) in staging.

Methods

Patients with histopathologically-proven cervical cancer and whole-body ¹⁸F-FDG PET/MRI obtained before definitive treatment were retrospectively registered. Local tumor spread, nodal involvement, and distant metastases were evaluated using PET/MRI or MRI dataset alone. Histopathology or clinical consensus with follow-up imaging were used as reference standard. Tumor SUVmax and ADC were measured and SUVmax/ADC ratio calculated. Are

SUBMITTER: Steiner A 

PROVIDER: S-EPMC7821517 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature