Task-based functional connectivity in aging: How task and connectivity methodology affect discovery of age effects.

ABSTRACT:

Introduction

Past studies have found that healthy aging has a significant effect on the organization and function of networks in the human brain. Many of these studies have examined how functional connectivity during one task or at rest is affected by aging; however, few studies have systematically examined how the effect of age on functional connectivity may vary as a function of choice of in-scanner task.

Methods

The present study included healthy adults between the ages of 20 and 80 and examined a variety of metrics of functional connectivity during performance of 11 in-scanner tasks, falling into 4 cognitive domains: vocabulary, processing speed, fluid reasoning, and episodic memory. Functional connectivity was assessed at three levels: average correlations within and be

SUBMITTER: Varangis E 

PROVIDER: S-EPMC7821554 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature