High fibrinogen-to-albumin ratio is associated with hemorrhagic transformation in acute ischemic stroke patients.

ABSTRACT:

Introduction

Hemorrhagic transformation (HT) is a complex and multifactorial complication among patients with acute ischemic stroke (AIS), and the inflammatory response has been considered as a risk factor for HT. We aimed to evaluate the stratification of FAR (fibrinogen-to-albumin ratio), an inflammatory biomarker, in HT patients.

Methods

A total of 256 consecutive stroke patients with HT and 256 age- and gender-matched stroke patients without HT were included in this study. HT during hospitalization was diagnosed by follow-up imaging assessment and was classified into hemorrhagic infarction (HI) and parenchymal hematoma (PH) according to the recommendations of European Cooperative Acute Stroke Study II classification. Blood samples were obtained at admission.

Results</

SUBMITTER: Ruan Y 

PROVIDER: S-EPMC7821560 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature