Resting-state default mode network connectivity in young individuals with Down syndrome.

ABSTRACT:

Background

Down syndrome (DS) is a chromosomal disorder that causes intellectual disability. Few studies have been conducted on functional connectivity using resting-state fMRI (functional magnetic resonance imaging) signals or more specifically, on the relevant structure and density of the default mode network (DMN). Although data on this issue have been reported in adult DS individuals (age: >45 years), the DMN properties in young DS individuals have not been studied. The aim of this study was to describe the density and structure of the DMN network from fMRI signals in young DS (age: <36 years).

Method

A sample of 22 young people with DS between the ages of 16 and 35 (M = 25.5 and SD = 5.1) was recruited in various centers for people with intellectual disability (ID). In

SUBMITTER: Figueroa-Jimenez MD 

PROVIDER: S-EPMC7821605 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature