Regulation of the antennal transcriptome of the dengue vector, Aedes aegypti, during the first gonotrophic cycle.

ABSTRACT:

Background

In the light of dengue being the fastest growing transmissible disease, there is a dire need to identify the mechanisms regulating the behaviour of the main vector Aedes aegypti. Disease transmission requires the female mosquito to acquire the pathogen from a blood meal during one gonotrophic cycle, and to pass it on in the next, and the capacity of the vector to maintain the disease relies on a sustained mosquito population.

Results

Using a comprehensive transcriptomic approach, we provide insight into the regulation of the odour-mediated host- and oviposition-seeking behaviours throughout the first gonotrophic cycle. We provide clear evidence that the age and state of the female affects antennal transcription differentially. Notably, the temporal- and state-depe

SUBMITTER: Hill SR 

PROVIDER: S-EPMC7821643 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature