Topical Tranexamic Acid to Reduce Postoperative Blood Loss in Total Knee Arthroplasty.

ABSTRACT:

Introduction

Total knee arthroplasty alleviates pain and restores function in patients with osteoarthritis of the knee, but it is associated with postoperative blood loss resulting in anemia and allogeneic blood transfusion in 10% to 38% of patients.

Step 1 prepare solution

Prepare tranexamic acid solution using aseptic technique.

Step 2 apply solution

Apply tranexamic acid solution to the open joint and soft-tissue surfaces.

Step 3 remove solution and close

Remove tranexamic acid, keeping the tourniquet inflated until the wound is closed and the dressing is applied.

Results & preop/postop images

We showed, in a prospective, double-blinded, placebo-controlled randomized trial, that topical application of tranexamic acid directly into the surgical wound p

SUBMITTER: Wong J 

PROVIDER: S-EPMC7821972 | biostudies-literature | 2011 Jun

REPOSITORIES: biostudies-literature