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Neuropathologic findings of patients with COVID-19: a systematic review.


ABSTRACT:

Background

Despite the expanding literature that discusses insights into the clinical picture and mechanisms by which the SARS-CoV-2 virus invades the nervous system, data on the neuropathologic findings of patients who died following SARS-CoV-2 infection is limited.

Methods

A broad literature search was done for published articles that reported on histopathological findings of the brain in patients with COVID-19 in PubMed by MEDLINE, Embase, CENTRAL by the Cochrane Library, and SCOPUS from December 31, 2019 to October 31, 2020.

Results

The systematic literature search strategy used resulted in a total of 1608 articles of which 14 were included in the analysis (PROSPERO registration number: CRD42020221022). There were ten case series, two case reports, one retrospecti

SUBMITTER: Pajo AT 

PROVIDER: S-EPMC7822400 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature