A novel procalcitonin-based score for detecting sepsis among critically ill patients.

ABSTRACT:

Background

Procalcitonin (PCT) has been widely investigated as an infection biomarker. The study aimed to prove that serum PCT, combining with other relevant variables, has an even better sepsis-detecting ability in critically ill patients.

Methods

We conducted a retrospective cohort study in a regional teaching hospital enrolling eligible patients admitted to intensive care units (ICU) between July 1, 2016, and December 31, 2016, and followed them until March 31, 2017. The primary outcome measurement was the occurrence of sepsis. We used multivariate logistic regression analysis to determine the independent factors for sepsis and constructed a novel PCT-based score containing these factors. The area under the receiver operating characteristics curve (AUROC) was applied to e

SUBMITTER: Tsui TL 

PROVIDER: S-EPMC7822524 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature