Estimating a Set of Mortality Risk Functions with Multiple Contributing Causes of Death.

ABSTRACT:

Background

There are few methodologic examples of how multiple causes of death may be summarized in cause-specific mortality analyses to address limitations of attributing death to a single underlying cause. We propose a cause-of-death weighting approach to estimate the set of risk functions of specific causes of mortality using both underlying and contributing cause-of-death information.

Methods

We constructed weights according to a user-specified function. Using data from four southern US human immunodeficiency virus (HIV) clinics, we constructed a cause of death-weighted Aalen-Johansen estimator of the cumulative incidence function to estimate risks of five specific causes of mortality in the full sample and by injection drug use history.

Results

Among 7740 HIV-pos

SUBMITTER: Breger TL 

PROVIDER: S-EPMC7822729 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature