The role of ICSI vs. conventional IVF for patients with advanced maternal age-a randomized controlled trial.

ABSTRACT:

Objectives

This study aimed to evaluate the role of intracytoplasmic sperm injection (ICSI) in the treatment of non-male factor infertile patients aged ≥ 39.

Methods

This is a single-center, prospective, randomized controlled clinical trial, between March 2018 and December 2019. Sixty-nine patients were recruited, and sixty patients participated in the study. Their ovaries were randomized prior to the beginning of the ovarian stimulation: the oocytes from one side (n = 257) were allocated to the ICSI (ICSI arm), while those of the contralateral side (n = 258) were allocated to conventional insemination (IVF arm). The fertilization rate per oocyte retrieved, number of zygotes (2PN), and cleavage-stage embryos were assessed and compared between the two study groups.

Results

SUBMITTER: Haas J 

PROVIDER: S-EPMC7822989 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature