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Clinical characteristics and outcomes of critically ill patients with COVID-19 in Kobe, Japan: a single-center, retrospective, observational study.


ABSTRACT:

Purpose

Coronavirus disease 2019 (COVID-19) has placed a great burden on critical care services worldwide. Data regarding critically ill COVID-19 patients and their demand of critical care services outside of initial COVID-19 epicenters are lacking. This study described clinical characteristics and outcomes of critically ill COVID-19 patients and the capacity of a COVID-19-dedicated intensive care unit (ICU) in Kobe, Japan.

Methods

This retrospective observational study included critically ill COVID-19 patients admitted to a 14-bed COVID-19-dedicated ICU in Kobe between March 3, 2020 and June 21, 2020. Clinical and daily ICU occupancy data were obtained from electrical medical records. The last follow-up day was June 28, 2020.

Results

Of 32 patients included, the median hospital follow-up period was 27 (interquartile range 19-50) days. The median age was 68 (57-76) years; 23 (72%) were men and 25 (78%) had at least one comorbidity. Nineteen (59%) patients received invasive mechanical ventilation for a median duration of 14 (8-27) days. Until all patients were discharged from the ICU on June 5, 2020, the median daily ICU occupancy was 50% (36-71%). As of June 28, 2020, six (19%) died during hospitalization. Of 26 (81%) survivors, 23 (72%) were discharged from the hospital and three (9%) remained in the hospital.

Conclusion

During the first months of the outbreak in Kobe, most critically ill patients were men aged ≥ 60 years with at least one comorbidity and on mechanical ventilation; the ICU capacity was not strained, and the case-fatality rate was 19%.

SUBMITTER: Ito J 

PROVIDER: S-EPMC7823169 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature

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Publications

Clinical characteristics and outcomes of critically ill patients with COVID-19 in Kobe, Japan: a single-center, retrospective, observational study.

Ito Jiro J   Seo Ryutaro R   Kawakami Daisuke D   Matsuoka Yoshinori Y   Ouchi Kenjiro K   Nonami Suguru S   Miyoshi Yusuke Y   Tatebe Masao M   Tsuchida Takahiro T   Asaka Yoko Y   Yanai Machi M   Ueta Hiroshi H   Shimozono Takahiro T   Mima Hiroyuki H   Doi Asako A   Tomii Keisuke K   Ariyoshi Koichi K  

Journal of anesthesia 20210123 2


<h4>Purpose</h4>Coronavirus disease 2019 (COVID-19) has placed a great burden on critical care services worldwide. Data regarding critically ill COVID-19 patients and their demand of critical care services outside of initial COVID-19 epicenters are lacking. This study described clinical characteristics and outcomes of critically ill COVID-19 patients and the capacity of a COVID-19-dedicated intensive care unit (ICU) in Kobe, Japan.<h4>Methods</h4>This retrospective observational study included c  ...[more]

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