Proteinuria in COVID-19: prevalence, characterization and prognostic role.

ABSTRACT:

Background

Proteinuria has been commonly reported in patients with COVID-19. However, only dipstick tests have been frequently used thus far. Here, the quantification and characterization of proteinuria were investigated and their association with mortality was assessed.

Methods

This retrospective, observational, single center study included 153 patients, hospitalized with COVID-19 between March 28th and April 30th, 2020, in whom total proteinuria and urinary α₁-microglobulin (a marker of tubular injury) were measured. Association with mortality was evaluated, with a follow-up until May 7th, 2020.

Results

According to the Kidney Disease Improving Global Outcomes staging, 14% (n = 21) of the patients had category 1 proteinuria (< 150 mg/g of urine creatinine

SUBMITTER: Huart J 

PROVIDER: S-EPMC7823174 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature