Hypercalcemia in Children Using the Ketogenic Diet: A Multicenter Study.

ABSTRACT:

Context

The ketogenic diet is associated with progressive skeletal demineralization, hypercalciuria, and nephrolithiasis. Acute hypercalcemia has been described as a newly recognized complication of this treatment.

Objective

To describe the clinical characteristics of acute hypercalcemia in children on the ketogenic diet through analysis of the presentation, response to treatment, and natural history in a large cohort of patients.

Design

A multicenter case series was performed including children who developed acute hypercalcemia while treated with the ketogenic diet. Information on clinical presentation, treatment, and course of this complication was collated centrally.

Results

There were 14 patients (median (range) age 6.3 (0.9 to 18) years) who developed hype

SUBMITTER: Hawkes CP 

PROVIDER: S-EPMC7823241 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature