Isolation and Characterization of Salmonella Jumbo-Phage pSal-SNUABM-04.

ABSTRACT: The increasing emergence of antimicrobial resistance has become a global issue. Therefore, many researchers have attempted to develop alternative antibiotics. One promising alternative is bacteriophage. In this study, we focused on a jumbo-phage infecting Salmonella isolated from exotic pet markets. Using a Salmonella strain isolated from reptiles as a host, we isolated and characterized the novel jumbo-bacteriophage pSal-SNUABM-04. This phage was investigated in terms of its morphology, host infectivity, growth and lysis kinetics, and genome. The phage was classified as Myoviridae based on its morphological traits and showed a comparatively wide host range. The lysis efficacy test showed that the phage can inhibit bacterial growth in the planktonic state. Genetic anal

SUBMITTER: Kwon J 

PROVIDER: S-EPMC7823757 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature