Relational Memory in the Early Stage of Psychosis: A 2-Year Follow-up Study.

ABSTRACT:

Background

Relational memory, the ability to bind information into complex memories, is moderately impaired in early psychosis and severely impaired in chronic schizophrenia, suggesting relational memory may worsen throughout the course of illness.

Methods

We examined relational memory in 66 early psychosis patients and 64 healthy control subjects, with 59 patients and 52 control subjects assessed longitudinally at baseline and 2-year follow-up. Relational memory was assessed with 2 complementary tasks, to test how individuals learn relationships between items (face-scene binding task) and make inferences about trained relationships (associative inference task).

Results

The early psychosis group showed impaired relational memory in both tasks relative to the healthy c

SUBMITTER: Avery SN 

PROVIDER: S-EPMC7825006 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature