Impact of Overweight and Obesity on US Papillary Thyroid Cancer Incidence Trends (1995-2015).

ABSTRACT:

Background

Since the early 1980s, papillary thyroid cancer (PTC) incidence rates and the prevalence of obesity, a risk factor for PTC, have increased substantially in the United States. We estimated the proportion of PTC incidence in the United States attributable to overweight and obesity during 1995-2015.

Methods

National Institutes of Health-AARP Diet and Health Study cohort data (n = 457 331 participants, 50-71 years and cancer-free at baseline) were used to estimate multivariable-adjusted hazard ratios (HRs) for PTC across body mass index categories. Population attributable fractions (PAFs) were calculated using estimated hazard ratios and annual overweight and obesity prevalence estimates from the National Health Interview Survey. PAF estimates were combined with Surve

SUBMITTER: Kitahara CM 

PROVIDER: S-EPMC7825478 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature